Recombinant Human Bone Morphogenetic Protein 2/BMP-2 (C012)

目录 规格 价格
【BMP-2产品说明】:
Recombinant Human Bone Morphogenetic Protein 2 is produced by our E.coli expression system and the target gene encoding Gln283-Arg396 is expressed.
【BMP-2质量控制】:
Measured by the cytolysis of MC3T3-E1 cells.
ED50 is less than 50 ng/ml. Specific Activity of 2.0 x 10^4 IU/mg
Greater than 95% as determined by reducing SDS-PAGE.
【BMP-2制剂】:
Lyophilized
【BMP-2保存】:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
【BMP-2复溶】:
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
【关于BMP-2】:
Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
参考文献

  • Tingting Wu, Haibo Zhou, Yongfeng Hong, Jing Li, Xinquan Jiang, and Hui Huang.
    miR-30 Family Members Negatively Regulate Osteoblast Differentiation.
    Journal of biological chemistry (2012)

  • Huiyong Zhu,1 Dan Yu,1 Ying Zhou,1 Chi Wang,2 Mengfei Gao,3 Hongliang Jiang,4 Huiming Wang.
    Biological activity of a nanofibrous barrier membrane containing bone morphogenetic protein formed by core-shell electrospinning as a sustained delivery vehicle†.
    J Biomed Mater Res (2013)

  • Sheng-Li Huang, Bo Wen, Wei-Guo, Hong-Wei Yan .
    Reconstruction of comminuted long-bone fracture using CF/CPC scaffolds manufactured by rapid prototyping.
    Med Sci Monit(2012)
For research use ONLY.