Recombinant Human Acyl-Protein Thioesterase 1/APT-1 (N-6His) (C097)

目录 规格 价格
【APT-1产品说明】:
Recombinant Human Acyl-Protein Thioesterase 1 is produced by our E.coli expression system and the target gene encoding Met1-Asp230 is expressed with a 6His tag at the N-terminus.
【APT-1质量控制】:
Greater than 95% as determined by reducing SDS-PAGE.
【APT-1制剂】:
Liquid
【APT-1保存】:
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
【关于APT-1】:
Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1 performs on biological membranes to regulate the multifunctional lysophospholipids. It hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. It hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS; in addition, it also has depalmitoylating activity and low lysophospholipase activity.
参考文献

  • Koyama K, Ogura Y, Nakai D, et al. .
    Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue.
    Drug Metabolism and Disposition(2014)
For research use ONLY.