Recombinant Human Bcl-2-Llike Protein 2/BCL2L2 (C-6His) (C105)

目录 规格 价格
【BCL2L2/Bc1-w产品说明】:
Recombinant Human B Cell Lymphoma/Leukemia w is produced by our E.coli expression system and the target gene encoding Ala2-Thr172 is expressed with a 6His tag at the C-terminus.
【BCL2L2/Bc1-w质量控制】:
Greater than 95% as determined by reducing SDS-PAGE.
【BCL2L2/Bc1-w制剂】:
Liquid
【BCL2L2/Bc1-w保存】:
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
【关于BCL2L2/Bc1-w】:
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
For research use ONLY.