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【B7-H3/CD276产品说明】:
Recombinant Mouse CD276 antigen is produced by our Mammalian expression system and the target gene encoding Val29-Phe244 is expressed with a 6His tag at the C-terminus.
【B7-H3/CD276质量控制】:
Greater than 95% as determined by reducing SDS-PAGE.
【B7-H3/CD276制剂】:
Lyophilized
【B7-H3/CD276保存】:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
【B7-H3/CD276复溶】:
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
【关于B7-H3/CD276】:
B7-H3, also known as CD276, is a member of the B7 family of costimulatory molecules. B7-H3 plays a potent role in both stimulatory and inhibitory effects on T-cell immunity. B7-H3 is expressed in T cells and B cells, dendritic cells, macrophages, liver, urothelium, and fetal kidney, and also been broadly detected in human cancer cells, including carcinomas of the colon, ovary, prostate, pancreas, kidney, and prostate, as well as urothelial carcinoma. In tumor, B7-H3 expression has been reported in several human cancers, which indicated an additional function of B7-H3 as a regulator of anti-tumor immunity. Statistical analysis in clinics showed that B7-H3 is an independent prognostic marker and associated with parameters in cancer progression.
For research use ONLY.