Recombinant Human N-Acetylglucosamine-6-Sulfatase/GNS (C-6His) (C354)

目录 规格 价格
【N-Acetylglucosamine-6-Sulfatase产品说明】:
Recombinant Human N-Acetylglucosamine-6-Sulfatase is produced by our Mammalian expression system and the target gene encoding Val37-Leu552 is expressed with a 6His tag at the C-terminus.
【N-Acetylglucosamine-6-Sulfatase质量控制】:
Greater than 95% as determined by reducing SDS-PAGE.
【N-Acetylglucosamine-6-Sulfatase制剂】:
Liquid
【N-Acetylglucosamine-6-Sulfatase保存】:
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
【关于N-Acetylglucosamine-6-Sulfatase】:
N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family. N-Acetylglucosamine-6-Sulfatase is required for the lysosomal degradation of the Glycosaminoglycans (GAG) Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase hydrolyzes the 6-Sulfate groups of the N-Acetyl-D-Glucosamine 6-Sulfate units of Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase binds 1 Calcium ion per subunit. N-Acetylglucosamine-6-Sulfatase deficiency are the cause of Mucopolysaccharidosis Type 3D (MPS3D), an inborn error leading to lysosomal accumulation of heparan sulfate. MPS3D has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations.
For research use ONLY.