Recombinant Mouse Macrophage Metalloelastase/MMP12 (C-6His) (C692)

目录 规格 价格
Recombinant Mouse Matrix Metalloproteinase 12 is produced by our Mammalian expression system and the target gene encoding Ala29-Cys473 is expressed with a 6His tag at the C-terminus.
Greater than 95% as determined by reducing SDS-PAGE.
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

  • LU Hai-bin1, WANG Shi-han, LI Qing-min, WANG Yong-sheng .
    Design, synthesis and evaluation of 6-oxo-1, 6-dihydropyrimidine-2,5-dicarboxamide derivatives as MMP 13 inhibitors.
    Chem. Res. Chin. Univ(2013)
For research use ONLY.