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Recombinant Mouse OX40/TNFRSF4/CD134 (N-Fc) (CK53)

目录 规格 价格
【OX40/TNFRSF4产品说明】:
Recombinant Mouse OX40L Receptor is produced by our Mammalian expression system and the target gene encoding Val20-Pro211 is expressed with a Fc tag at the N-terminus.
【OX40/TNFRSF4质量控制】:
Greater than 95% as determined by reducing SDS-PAGE.
【OX40/TNFRSF4制剂】:
Lyophilized
【OX40/TNFRSF4保存】:
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
【OX40/TNFRSF4复溶】:
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
【关于OX40/TNFRSF4】:
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
For research use ONLY.